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Descrição
Vitamin D is a fat-soluble vitamin essential for maintaining calcium metabolism.
Vitamin D3 (cholecalciferol) can be synthesized by humans through exposure to ultraviolet B (UVB) rays, i.e., through daily sunlight, or obtained from food. Plants synthesize ergosterol, a substance similar to calciferol, which is converted to vitamin D2 (ergocalciferol) by the action of ultraviolet light.
Foods containing vitamin D include fatty fish, liver, and egg yolks. Cod liver oil is a particularly important source of this vitamin. Regular consumption of these foods, however, rarely corresponds to a typical diet. Therefore, dietary vitamin D intake provides only a small portion of what is needed. When exposure to UVB radiation is insufficient for the synthesis of adequate amounts of vitamin D3, adequate dietary vitamin D intake is essential for health.
Vitamin D is biologically inactive and must be metabolized—that is, transformed into its biologically active form—to be absorbed. After synthesis or ingestion, vitamin D is absorbed and transported through the bloodstream to the liver, where it is hydroxylated to form 25-hydroxyvitamin D, the main circulating form of this vitamin. Increased exposure to sunlight or increased vitamin D intake increases serum 25-hydroxyvitamin D levels, making its serum concentration a useful indicator of vitamin D nutritional status.
In the kidney, the enzyme 25-hydroxyvitamin D3-1-hydroxylase catalyzes a second hydroxylation of 25-hydroxyvitamin D, resulting in the formation of 1,25-hydroxyvitamin D (calcitriol, 1a,25-dihydroxyvitamin D), which is the more potent form of vitamin D.
Most of the physiological effects of vitamin D3 in the human body are related to the activity of 1,25-dihydroxyvitamin D3. -
Disclaimer
Bioself Natura Ltda. is not responsible for any discrepancies and/or changes in the product information provided by the supplier/manufacturer on the website, as stated on the product labels. Therefore, we recommend that you always read the mandatory and/or voluntary information on product labels before using or consuming them.
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Descrição
Vitamin D is a fat-soluble vitamin essential for maintaining calcium metabolism.
Vitamin D3 (cholecalciferol) can be synthesized by humans through exposure to ultraviolet B (UVB) rays, i.e., through daily sunlight, or obtained from food. Plants synthesize ergosterol, a substance similar to calciferol, which is converted to vitamin D2 (ergocalciferol) by the action of ultraviolet light.
Foods containing vitamin D include fatty fish, liver, and egg yolks. Cod liver oil is a particularly important source of this vitamin. Regular consumption of these foods, however, rarely corresponds to a typical diet. Therefore, dietary vitamin D intake provides only a small portion of what is needed. When exposure to UVB radiation is insufficient for the synthesis of adequate amounts of vitamin D3, adequate dietary vitamin D intake is essential for health.
Vitamin D is biologically inactive and must be metabolized—that is, transformed into its biologically active form—to be absorbed. After synthesis or ingestion, vitamin D is absorbed and transported through the bloodstream to the liver, where it is hydroxylated to form 25-hydroxyvitamin D, the main circulating form of this vitamin. Increased exposure to sunlight or increased vitamin D intake increases serum 25-hydroxyvitamin D levels, making its serum concentration a useful indicator of vitamin D nutritional status.
In the kidney, the enzyme 25-hydroxyvitamin D3-1-hydroxylase catalyzes a second hydroxylation of 25-hydroxyvitamin D, resulting in the formation of 1,25-hydroxyvitamin D (calcitriol, 1a,25-dihydroxyvitamin D), which is the more potent form of vitamin D.
Most of the physiological effects of vitamin D3 in the human body are related to the activity of 1,25-dihydroxyvitamin D3. -
Disclaimer
Bioself Natura Ltda. is not responsible for any discrepancies and/or changes in the product information provided by the supplier/manufacturer on the website, as stated on the product labels. Therefore, we recommend that you always read the mandatory and/or voluntary information on product labels before using or consuming them.